Summary for ENCSR372CKT

Summary

Status
released
Description
Functional characterization series for dCas9-ZNF705-KRAB/CRISPRi tiling proliferation screens at a subset of cCREs around essential genes
Donor diversity
single
Assay
proliferation CRISPR screen
Biosample summary
Homo sapiens K562, 21 days post-nucleic acid delivery time genetically modified (insertion) using transduction, using CRISPRi (sgRNA)
Diseases
Not reported
Treatments
Puromycin
Elements references
Tiling modality
peak tiling

Attribution

ENCODE4 project
Lab
Will Greenleaf, Stanford
Award
UM1HG009436 (Will Greenleaf, Stanford)
Project
ENCODE
Aliases
will-greenleaf:K562_DHS_BatchTiling_Growth_dCas9-ZNF705-KRAB
External resources
None submitted

Experiments in ENCSR372CKT

Experiments
1 experiment
Accession
Assay
Examined loci
Biosample summary
Lab
Status
Cart
ENCSR007UZQproliferation CRISPR screenHomo sapiens K562, 21 days post-nucleic acid delivery time genetically modified (insertion) using transduction, using CRISPRi (sgRNA)Will Greenleaf, Stanford
released
Control experiments
1 control experiment
Accession
Control type
Biosample summary
Lab
Status
Cart
ENCSR024GFNcontrolWill Greenleaf, Stanford
released